Systems-level computational modeling demonstrates fuel selection switching in high capacity running and low capacity running rats
Fig 2
Metabolic transport fluxes for HCR and LCR rats.
Transport fluxes were obtained during a previously published graded treadmill experiment [30] and converted to molar quantities. In this experiment, HCR and LCR rats were ran at an increasing treadmill speed (every 2 minutes) until exhaustion. (A) O2 uptake fluxes for HCR (blue) and LCR (red) rats. (B) CO2 output fluxes for HCR (blue) and LCR (red) rats. (C) Estimated carbohydrate uptake flux for HCR (blue) and LCR (red) rats. (D) Estimated FA uptake fluxes for HCR (blue) and LCR (red) rats.