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A computational model for how cells choose temporal or spatial sensing during chemotaxis

Fig 6

Noise in the external chemoattractant favors temporal sensing.

Results for the incoherent feedforward circuit (left) and negative integral feedback circuit (right). (a) Fraction of parameters that yielded OT > 0 (green) and OS > 0 (red) for all the stochastics runs at different amount of noise, η, for β = 0.25 (circle), β = 1.0 (diamonds) and β = 4.0 (triangles). (b) Fraction of parameters that chose temporal sensing (green), spatial sensing (red) and failure in sensing (black) at different amount of noise for β = 0.25 (first column), β = 1.0 (second column) and β = 4.0 (third column).

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1005966.g006