A computational model for how cells choose temporal or spatial sensing during chemotaxis
Fig 5
Choice of temporal versus spatial sensing.
(a) Parameter space for choice of temporal versus spatial sensing. (b) Plot of log(cell diameter, d) versus log(cell velocity, v) for chemotactic cells. The respective cells are as follows; In the flagellar group (green dots) are a: Vibriocholarae, b: Escherichia coli, c: Helicobacter pylori, d: Pseudomonas aeruginosa, e: Salmonella typhimurium, f: Marine Vibrioid bacteria sampled from Niva Bay, g: Thiovulum majus, h: Chlamydomonas reinhardtii, i: Sperm (human) and j: Sperm (Sea urchin). In the cilia group (blue diamonds) are k: Tetrahymena thermophila and l: Paramecium. In the lamellipodia/filopodia group (black stars) are m: T cell, n: Neutrophil, o: Hemocyte, p: B cell, q: Dendritic cell, r: Endothelial cell, s: Fibroblast and t: Border cells. In the pseudpodia group (red squares) are u: Dictyostelium discoideum, v: Acanthamoeba castellanii, w: Amoeba proteus and x: Chaos carolinensis. Assuming a signaling rate, lBC, occurring between 0.2s−1 to 5s−1 then the yellow region will be the separating boundary between cells with high and low values of β. The black line is the decision boundary for lBC = 1s−1.