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A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal

Fig 3

Breakdown of no-calls made by SGZ.

Reasons behind no-calls made by SGZ are shown for (left) all variants in 30 lung and colon samples and (right) 17 somatic hotspot mutations and 20 common germline variants within 20,182 clinical samples.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1005965.g003