A mathematical model for IL-6-mediated, stem cell driven tumor growth and targeted treatment
Fig 6
Model prediction of the temporal changes in the factional occupancy of IL-6 receptors on CSCs, ϕS, as the IL-6 secretion rate by tumor cells, ρ, varies from its baseline value (ρ = 7 × 10−7 fmol/cell/day) to the value that leads to 90% fractional occupancy (5.35 × 10−6 fmol/cell/day).