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Optimal number of spacers in CRISPR arrays

Fig 5

Effect of parameters on the optimal number of spacers and the maximal survival probability.

The optimal number of spacers and corresponding survival probability as functions of one of the array-unrelated parameters: (A) As function of mutation probability 1 − μ, other parameters are β = 1 and χ = 1.4. (B) As function of binding efficiency β, other parameters are μ = 0.9 and χ = 1.4. (C) As function of interference efficiency χ, other parameters μ = 0.9 and β = 1. The average number of viral infections was rNt = 5 in all panels.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1005891.g005