A systematic atlas of chaperome deregulation topologies across the human cancer landscape
Fig 6
Polar maps of chaperome shifts in human cancers.
Polar plot visualization as novel quantitative and contextual representation of M-scores, new Meta-PCA derived quantitative indices of relative disease gene expression shifts of chaperome functional processes compared to normal tissue counterparts. Examples representative of Group 1 cancers, lung adenocarcinoma (LUAD) (A), and Group 2 cancers, pheochromocytoma and paraganglioma (PCPG) (B) are shown. Blue (normal) and red lines (cancer), sample means. Halos, confidence interval at the 90% quantile range (5%–95%). LUAD (lung adenocarcinoma), PCPG (pheochromocytoma and paraganglioma).