Thalamocortical control of propofol phase-amplitude coupling
Fig 4
Propofol potentiation of gGABAA and τGABAA enables sustained alpha oscillations on the gH-background excitation plane.
(A) Model network and behavioral regimes of simulations across the gH-background excitation plane under baseline. See Fig 3 for behavior regime legend. (B) Model network and behavioral regimes of simulations across the gH-background excitation plane under low-dose propofol. Note the presence of sustained alpha (red) simulations. (C) Model network and behavioral regimes of simulations across the gH-background excitation plane under high-dose propofol.