Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs
Fig 6
An example of a pseudo-energy calculation using the NCM model.
ΔGjunction is evaluated for each pair of NCMs that share an edge, i.e. the ones that have an overlapping base pair. This term depends on the identities of the two NCMs (that is, the length of the 5’ and 3’ cycles for a double-stranded NCM, or the total length for a single-stranded NCM), and the nucleotides in the common base pair. This term is evaluated for the junction of NCM a with NCM b, NCM b with NCM c, and NCM c with NCM d.