Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs
Fig 2
Benchmark of single-sequence prediction of canonical base pairs.
(A) Prediction accuracy of the lowest free energy structure, evaluated on canonical pairs. (B) Prediction with CycleFold, using structures composed of highly probable canonical pairs. Sensitivity and PPV are reported for structures with probability greater than a threshold labeled on the plot). This demonstrates that the threshold stringency provides a tradeoff in terms of sensitivity and PPV.