Insight into glucocorticoid receptor signalling through interactome model analysis
Fig 3
Interaction matrix for GEB052 model.
Figure adapted from the CNA-generated interaction matrix. The right-hand y-axis shows the number of reactions that each node is involved in, whilst the left-hand y axis shows the nodes present within the model. For the right-hand axis, numbers in brackets are equal to the number of nodes it activates, the number of nodes it inhibits, and the number of nodes it is regulated by. All model nodes for all model edges are assigned a value in the interaction matrix. Black is equivalent to no participation, whilst blue means the node is affected (i.e. regulated) by the interaction. Red means the node has an inhibition input whilst green means the node has a stimulatory input.