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Prediction of HIV-1 sensitivity to broadly neutralizing antibodies shows a trend towards resistance over time

Fig 4

Association between coreceptor usage and neutralization sensitivity.

Relative number of resistant (orange) and susceptible (blue) strains with regard to their coreceptor usage for the bNAbs PGT128 and VRC-PG04, as well as for VRC01, PG9, and PG16. Statistical significance was assessed with a two-sided Fisher’s exact test. Data for VRC01, VRC-PG04, PG9 and PG16 was taken from Pfeifer et al. [63].

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1005789.g004