Prediction of HIV-1 sensitivity to broadly neutralizing antibodies shows a trend towards resistance over time
Fig 3
Characteristics of the non-B subtype HIV variants over time.
Predicted neutralization sensitivity of non-B subtype HIV-1 variants to bNAbs over time. A - D: the predicted neutralization sensitivity of HIV-1 samples of the non-B subtype to the bNAbs 3BNC117, 35O22, PGT121, and PG16. E: the ratio of R5-tropic and X4-capable non-B subtype HIV-1 variants in the Los Alamos HIV sequence database over the six time periods. F: predicted neutralization sensitivity of R5-tropic variants of the non-B subtype to PG16.