A continuum-mechanical skeletal muscle model including actin-titin interaction predicts stable contractions on the descending limb of the force-length relation
Fig 9
Coefficient of variation (CoV; standard deviation/mean*100%) of the half-sarcomere lengths during an isometric contraction at muscle length L/L0 = 1.2, for models (blue line), MFv (red line), MATI (black solid line) and
(black dashed line).
While actin—titin interactions can damp the magnitude of half-sarcomere—length heterogeneities, the force-velocity relation damps the their temporal evolution.