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A continuum-mechanical skeletal muscle model including actin-titin interaction predicts stable contractions on the descending limb of the force-length relation

Fig 4

Top: Isometric force responses of the microscopic half-sarcomere model due to different stimulations. Single—twitch (black), submaximal contraction at 20 Hz (red), and tetanic contraction at 100 Hz (blue). Bottom: Force—frequency relation of the half-sarcomere model. Under conditions of not completely fused twitches, the range between the minimum and maximum values of the active force is shown.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1005773.g004