Mathematical modeling and quantitative analysis of HIV-1 Gag trafficking and polymerization
Fig 5
Comparison between the simulation results and experimental data for Gag-G2A.
Gagi(i = 1, 2, ⋯, 6) denotes a polymer with i monomers. The left side illustrates the comparisons between the simulation and experimentally measured concentrations for monomers and dimers in the cytoplasm. The right side shows the differences between the simulation and experimentally measured concentrations with the six types of polymers at the plasma membrane. The concentration of each type of polymer was normalized by dividing by the concentration of Gag monomer in the cytoplasm.