Population FBA predicts metabolic phenotypes in yeast
Fig 4
Depiction of yeast central metabolism covering glycolysis, TCA cycle and electron transport chain.
Values next to reactions in the plot represent fluxes through those reactions. Values between parenthesis are derived from our simulations using yeast 7.6 model with (red) and without (black) constraints on acetate (Ac) and glycerol (Gly) secretion, whereas values between brackets (green) were taken from experimental 13C measurements [40]. A mapping between abbreviated reaction names and full names can be found in Table A4 in S1 Text. Constraint on ubiquinole-ferricytochrome c reductase reaction causes the Crabtree effect and is marked by red star.