Population FBA predicts metabolic phenotypes in yeast
Fig 2
(A) Predicted growth rate distribution from Population FBA analysis of E. coli with correlated sampling of protein distributions. Experimental bulk growth rate marked by black dashed line [34]. (B) Predicted growth rate distributions for 100,000 cells in glucose synthetic defined medium (SD) (blue). Also shown is the experimentally measured growth rate distribution in SD medium and 13C medium [38, 40]. Simulated growth curves have correlated sampling from protein distributions and mRNA microarrays. Growth rate distributions are made by binning growth rates into 50 bins.