Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity
Fig 2
Comparison between motifs predicted by our algorithm and known motifs.
A: Comparison with IEDB motifs for 44 HLA-I binding motifs identified with the fully unsupervised approach. Alleles without previously documented ligands are highlighted in red. For HLA-B56:01, the three known ligands are shown. B: Comparison with motifs obtained from mono-allelic cell lines [31]. C: Motif identified with the semi-supervised approach.