Limb-Enhancer Genie: An accessible resource of accurate enhancer predictions in the developing limb
Fig 3
Biological interpretation of the chromatin models based on feature importance.
For each macro-category (on the far left), each dataset considered is indicated (stage, structure and reference publication are specified), followed by three distinct plots showing (left to right): (1) a box plot overlaid to a violin plot showing the distribution of the coefficients assigned to each particular feature by LASSO; (2) the selection probability as estimated by Bootstrap LASSO (darker shades of green indicating higher probability); (3) the feature importance estimated as mean decrease in accuracy by RF (separately for the positive and the negative classes, indicated by red and light blue bars, respectively).