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Altering neuronal excitability to preserve network connectivity in a computational model of Alzheimer's disease

Fig 5

Network topology.

A) Network analysis: comparison of normalized clustering coefficient (gamma) values over time for the different interventions, indicating local connectivity strength. B) Comparison of modularity (community presence) over time for the different interventions. C) Comparison of algebraic connectivity values over time for the different interventions, indicating network robustness. D) Comparison of MST leaf number values over time for the different interventions, reflecting network hub presence. Error bars indicate the standard deviation over the total number of runs of the various strategies.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1005707.g005