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Upregulation of an inward rectifying K⁺ channel can rescue slow Ca²⁺ oscillations in K(ATP) channel deficient pancreatic islets

Fig 2

The Kir2.1 channel conductance depends on voltage and the cAMP concentration.

(A) Voltage-dependent blockade of the Kir2.1 current. (B) cAMP-dependent activation of the Kir2.1 current.

doi: https://doi.org/10.1371/journal.pcbi.1005686.g002