Interactions between the tumor and the blood systemic response of breast cancer patients
Fig 4
Subtype-Specific Matched Interactions across Tissue (ssMIxT).
(A) Schematic of ssMIxT analysis (B) Significant associations between modules in SR and tumor from BC patients by subtype (MIxT statistic, p-value < 0.005). SR and tumor modules with top pathway enrichment keywords are presented in rows and columns, respectively. Subtype(s) in which the significant associations are found are indicated in the table. Blue and red borders correspond to negative and positive correlations between ranksums, respectively. Findings discussed in the text are highlighted in orange.