Interactions between the tumor and the blood systemic response of breast cancer patients
Fig 1
Individual characteristics and SR markers of BC subtypes.
(A) Collection of biospecimen from BC patients and controls. (B) Individual characteristics of BC patients and controls. (C) Parallel plot displaying the repartition of BC patients across RNA-based subtyping schemes. (D) Sparse hierarchical clustering of BC patients based on genes expressed in tumor (upper) and the patient SR (lower). Clinicopathological and subtypes attributes are presented below the dendrogram. (E) Significant gene markers of subtypes in SR (false discovery rate, fdr ≤ 0.2). Blue and red shade correspond to under- and over- expression of the marker in a given subtype vs the others, respectively. Shading is proportional to the level of significance of the gene marker.