Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach
Fig 8
Simulated effects of non-compliance on bacterial load following treatment.
Treatment simulations are repeated but programmed to randomly miss 20% of doses. Graph shows mean and standard error of total bacteria (CFU) after 180 days of treatment with MXF, GFX or LVX for 100% compliance (solid bars) or 20% missed doses (hashed bars). *: p-value < 0.05, **: p-value < 0.005.