Classification and analysis of a large collection of in vivo bioassay descriptions
Fig 4
ATC classes of approved drugs tested in in vivo efficacy assays.
The dendrogram represents the Anatomical Therapeutic Chemical (ATC) drug hierarchy and the coverage of various drug classes in the ChEMBL in vivo dataset. The height and color of bars on the circular bar plot (external ring) represent the number of assays involving drugs assigned given ATC code (level 2 of the ATC classification system). Most common ATC level 2 classes corresponding to different therapeutic/pharmacological subgroups are highlighted.