MFPred: Rapid and accurate prediction of protein-peptide recognition multispecificity using self-consistent mean field theory
Fig 2
Comparison of backbone ensemble generation methods.
(a) Experimental specificity profiles. (b) MFPred on FastRelax backbone ensemble. The p-value of the JSD for a given position is represented by the color of the square under that position; white denotes a p-value > 0.5 and dark blue denotes a p-value of 0. A given circle to the right of a profile represents the cosine similarity (white) and AUC (black) of that profile. The ROC plots beneath each profile depict the SSAL calculation via the experimental ROC (blue) and predicted ROC (red) with their respective AUC values. (c) MFPred on FlexPepDock backbone ensemble. (d) MFPred on Backrub backbone ensemble.