Inferring oscillatory modulation in neural spike trains
Fig 12
Motor cortical neuron (neuron 1, Figs 10 and 11) shows changing relationship to LFP theta oscillation in different trials.
A) The posterior distributions of the mixture weight of the weakly modulated L trials, and relative modulation strength of the strongly modulated H trials. B) PSTHL (blue) and PSTHH (pink) overlap one another, showing no difference in average firing rate. C) LFP theta amplitudes calculated for all L and H trials on a per trial basis. Difference between cumulative distributions of per trial LFP theta amplitude not significant, p < 0.78, 2 sample KS-test. D) Top, the 33 (187) trials classified as weakly (strongly) modulated trials, blue (pink) dots, top. Bottom, the SP histogram calculated from L (H) trials, left (right). Inference of modulation strength using the spike train alone corresponds to the modulation strength to LFP theta. Circular statistics RL = 0.06 ± 0.01 and RH = 0.16 ± 0.01 are significantly different, bootstrap test p < 7 × 10−4.