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Reduction of multiscale stochastic biochemical reaction networks using exact moment derivation

Fig 8

Trajectories of the full model, the EMB model and the AMB model of the positive feedback loop with decoys.

(A-B) The lines and colored ranges represent E(XT) and E(XT) ± SD(XT)/2 of 104 stochastic simulations when αA = 10 and α0 = 4. Here Xi(0) = 0. (C-D) When αA = 20 and α0 = 8, so that overall XT is greater than the total number of decoy sites (i.e N = 10), the AMB model also becomes accurate.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1005571.g008