Chemomechanical regulation of myosin Ic cross-bridges: Deducing the elastic properties of an ensemble from single-molecule mechanisms
Fig 4
Effective force-velocity relation.
The effective velocity v depends on the force F and on the actin concentrations. A large actin availability enhances the binding of the myosin head and therefore decreases the cycling time, which in turn increases the velocity. The inset shows the effective velocity in the absence of force as a function of the actin concentration.