Combining inferred regulatory and reconstructed metabolic networks enhances phenotype prediction in yeast
Table 1
Comparison of PROM and IDREAM predicted growth ratio with experiments under glucose minimal medium.
The ratio of mutant vs. wild-type growth rate was compared with the growth ratio for 119 TF knockouts previously measured by Sauer Lab. There were 51 TFs in common between the two integrative models, so we distinguish PROM by TF90 (the whole YEASTRACT-based model) and TF51 (the portion of the YEASTRACT-based model that overlaps with that from IDREAM).