Amino acid composition predicts prion activity
Fig 3
Comparison of amino acid weights for different methods.
(a) the weights for pRANK over the Alberti dataset; (b) the pRANK weights in proteome wide evaluation; (c) shows the log-odds ratio, obtained by Angarica et al., of the frequencies of occurrence of different amino acids in prion domains in the yeast prions relative to their corresponding background frequencies in the protein universe. Figure (d) shows the log-odds ratios obtained experimentally by the random mutagenesis experiment by Toombs et al.