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Functional asymmetry and plasticity of electrical synapses interconnecting neurons through a 36-state model of gap junction channel gating

Fig 7

Changes of junctional conductance in HeLa cells expressing Cx45 during bipolar and monopolar stimulation.

A) Junctional current (Ij) and conductance (gj) records obtained in response to repeated bipolar voltage (Vj) stimuli of –85 and +85 mV in amplitude; amplitude and duration of voltage spikes and current responses can be seen in the insets. B) The same as in (A) but unipolar –85 mV instead of bipolar stimuli were applied. Insets (grey background) above 7A and B show applied Vj stimuli and registered Ij values at enhanced resolution. The values of gj were estimated from gj = Ij/Vj.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1005464.g007