redGEM: Systematic reduction and analysis of genome-scale metabolic reconstructions for development of consistent core metabolic models
Fig 3
The synthesis of histidine from core carbon network.
Histidine synthesis starts from ribose-5-phosphate (R5P) from Pentose Phosphate Pathway, and consists of 10 reaction steps. Not all reactions of core network are shown. Orange reactions form the linear pathways for histidine as defined in databases. Metabolites colored with green are core metabolites, whereas orange and purple metabolites are non-core. The non-core metabolites along the linear pathway for histidine synthesis are balanced by the purple reactions.