Fast online deconvolution of calcium imaging data
Fig 4
OASIS produces the same high quality results as convex solvers at least an order of magnitude faster.
(A) Raw and inferred traces for simulated AR(1) data, (B) simulated AR(2) and (C) real data from [36] fitted with an AR(2) model. OASIS solves Eq (3) exactly for AR(1) and just approximately for AR(2) processes, nevertheless well extracting spikes. (D) Computation time for simulated AR(1) data with given λ (blue circles, Eq 3) or inference with hard noise constraint (green x, Eq 15). GUROBI failed on the noise constrained problem. The inset shows the same data in logarithmic scale. (E) Computation time for simulated AR(2) data. (F) Normalized computation time of OASIS for simulated AR(1) data with given λ (blue circles, Eq 3) and inference with hard noise constraint on full data (green x, Eq 15) or small initial batch followed by processing in online mode (orange crosses).