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Modelling T cell proliferation: Dynamics heterogeneity depending on cell differentiation, age, and genetic background

Fig 4

Proliferation rates and cell cycle phase durations in thymus and spleen.

Proliferation rates (%/day), G0/G1 and G2/M phase durations (in days) in B6 and FVB mice (n = 4 per group) according to age (2 and 18 months) in whole thymus (left) and whole spleen (right). Values are indicated in the box plot, the median is the 50th percentile, the lower and upper limits of the box are the 25th and 75th percentiles and the whiskers indicate 1.5x(interquartile range). *: p<0.05. **: p<0.01. (See Materials and Methods section for statistical tests used). Statistics are for proliferation rates only. Mean values and SD are given in S1 Table.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1005417.g004