Bistable front dynamics in a contractile medium: Travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions
Fig 4
The width of the contractile zone (with higher concentrations of RhoA and NMIIA), defined as the integral of the RhoA concentration over the whole domain, as a function of time, starting from a localized initial condition for a range of different contraction strengths (Pe = 2 to 16).
Note, that i) the slope (i.e. propagation speed) decreases as Pe is increased and there is a transition to a stationary contractile zone when Pe > 10. (α = 1, κ1 = κ2 = 0.2, K = 1); ii) the curves corresponding to Pe = 0–10 propagate with constant speed until they reach the end of the computational domain.