Unifying view of mechanical and functional hotspots across class A GPCRs
Fig 2
Color-coded profile of the average bridging score.
Amino acids in a reference GPCR structure (rhodopsin, PDB ID: 1F88) are color-coded according to the mechanical bridging score averaged over all receptors (blue to red from low to high scores). Residues shown in grey are those with no equivalent positions across the receptors’ ensemble. The top ten ranking sites, listed in the first column of Table 2, are labelled and highlighted with yellow beads in the inset.