Two dynamic regimes in the human gut microbiome
Fig 7
(A) shows decay in the number of Dirichelet multinomial mixture model (DMM) states as the sparcity of the time series is increased for the top 50 most abundant OTUs from each time series and for the 76 abundant OTUs shared across all four time series. The plateau is at 6 states for both methods (grey dashed line). (B) shows state classifications for samples taken from all four individuals (top 50 OTUs from each time series sampled at every 11th time point). States are largely unique to individuals (i.e. colors indicate unique states), with the exception of a single time point in the DA series that was assigned to a state (blue) that is dominant in DB.