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Effects of FGFR2 kinase activation loop dynamics on catalytic activity

Fig 4

Region of ¹⁵N HSQC of FGFR2 kinase.

Curved arrows indicate chemical shift perturbations that occur to the Arg664 shift as ATP analog is added. Black/blue spectra are of the unphosphorylated kinase, while red/purple spectra are of the phosphorylated kinase.

doi: https://doi.org/10.1371/journal.pcbi.1005360.g004