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Is the Conformational Ensemble of Alzheimer’s Aβ10-40 Peptide Force Field Dependent?

Fig 6

Aβ radius of gyration in different force fields.

Probability distributions, P(Rg), for the radius of gyration Rg of Aβ10-40 peptide computed for five force fields. Vertical bars represent sampling errors. The plots show that, in contrast to C36, C36s, and C22cmap force fields, C22* and OPLS-AA predict collapsed peptide structures.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1005314.g006