Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations
Fig 5
The Caenorhabditis elegans glucosamine-6-phosphate N-acetyltransferase (Gna1) complexed with CoA and N-acetylglucosamine-6-phosphate (GlcNAc6p) (pdb_id: 4ag9) [84].
Gna1 was assigned to node 12 of the hierarchy. A. Structural locations of acetylase residues (yellow) and node 12-specific residues (red). B. Node 12-specific residues involved in substrate binding. These residue positions are indicated in Fig 4 (as red dots above column positions). C. Node 12-specific residues associated with the homodimeric interface.