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A General Shear-Dependent Model for Thrombus Formation

Fig 7

Simulation results for platelet aggregation at high shear rates inside an 80% stenosis, where the undisturbed maximum wall shear rate is 8,000 s−1.

(a) View normal to the flow direction, and (b) view from above. Color coding for particles is the same as in Fig 3. (c) Normalized density of adhered platelets throughout the stenosis along the flow direction vs. normalized axial location. The density is normalized by the number of adhered platelets at the inlet, and axial distance is normalized by the length of the stenosis. Simulation results (−□−) are based on the activation delay time τact = 6 ± 3ms, and the error bars are computed based on 5 simulations with the same τact; experimental data (−○−) are extracted from Westein et al. [14] and plotted for comparison.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1005291.g007