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Tissue-Specificity of Gene Expression Diverges Slowly between Orthologs, and Rapidly between Paralogs

Fig 2

Pearson correlation of tissue-specificity focusing on a) human and b) mouse. X-axis, divergence time in million years between the genes compared; Y-axis, Pearson correlation between values of τ over genes. In red, the correlation of orthologs between the focal species and other species; representative species are noted above the figure; there are several points when there are several datasets for a same species, e.g. four for mouse (Table 1); the size of red circles is proportional to the number of tissues used for calculation of tissue-specificity. In blue, the correlation of paralogs in the focal species, according to the date of duplication; representative taxonomic groups for this dating are noted under the figure; the size of blue circles is proportional to the number of genes in the paralog group.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1005274.g002