A Stochastic Model of the Yeast Cell Cycle Reveals Roles for Feedback Regulation in Limiting Cellular Variability
Fig 8
Mutant phenotypes in glucose medium.
A (daughter) and B (mother) cells. The average of six cell cycle properties obtained from ‘computational cell culture’ simulations of WT cells and nine different mutant strains in glucose medium (μ = 0.007 min−1). Cell volumes in fL and phase durations in min. C (daughter) and D (mother) cells. The color bars indicate the percentage change in CV, relative to WT cells, of selected cell cycle properties (bottom) for a variety of mutant strains (left side). E. The number doubling times of ‘computational cell cultures’ are clustered for WT and mutant strains, showing largest variability among cultures of cdh1Δ cells.