A Stochastic Model of the Yeast Cell Cycle Reveals Roles for Feedback Regulation in Limiting Cellular Variability
Fig 4
mRNA histograms for a population of budding yeast cells.
A. Simulations for μ = 0.007 min−1 mimicking growth in glucose medium. The average number of mRNA molecules, <N>, for each gene is reported on the histogram. B. Joint distributions of mRNAs in individual cells. C. Comparison of model-predicted joint distributions (bottom row) with experimentally measured joint distributions (top row). For details of the experimental measurements, see Materials and Methods.