Beyond the Hypercube: Evolutionary Accessibility of Fitness Landscapes with Realistic Mutational Networks
Fig 4
Accessibility strongly depends on the initial fitness.
(a) Average number of accessible pathways as a function of initial fitness f0 for different K and for N = 220. Shaded areas represent standard errors. (b) Accessibility A as a function of initial fitness f0 for different K and for N = 228. A steep decrease in accessibility at some critical f0 (dashed line) indicates that the probability of reaching the best-fit genotype can be very sensitive to the initial fitness.