WORMHOLE: Novel Least Diverged Ortholog Prediction through Machine Learning
Fig 3
Performance of WORMHOLE SVMs generalizes across species.
Box and whisker plot representing the harmonic mean of precision and recall for each WORMHOLE SVM trained on PANTHER LDOs between one pair of query and target species when applied to predict PANTHER LDOs between each other pair of query and target species. Values represent the maximum harmonic mean for each pair of query and target species (WORMHOLE Score ≥ 0.5). Training data sets are ordered by median harmonic mean. The box labelled "same pair" shows the performance of each model when applied to predict LDOs within the same species pair used to train that model (with cross-validation).