PreTIS: A Tool to Predict Non-canonical 5’ UTR Translational Initiation Sites in Human and Mouse
Fig 7
In silico mutation analysis considering all 3,566 genes of the HEK293 dataset.
The flanking sequences of all possible start sites in the HEK293 dataset were mutated. Shown is the difference in the predicted initiation confidence (ICdifference = ICmutation − ICwildtype). Positions -3 and -12 are prevalent and seem to have the largest influence on the prediction. Positions at the start site were not mutated.