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Dynamic Cholesterol-Conditioned Dimerization of the G Protein Coupled Chemokine Receptor Type 4

Fig 8

Relative orientation angles used to describe the orientation of the monomers in the receptor dimer.

β describes the position of monomer B with respect to monomer A, φ is the rotation of monomer B around its z-axis, χ the angle under which monomer B “sees” monomer A. The axes x and y were placed into the monomer in a way that the symmetric TM5,6/TM5,6 dimer results in β = 0 and χ = 0.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1005169.g008